Tiktoking COVID-19 with frontline workers.

Introduction/Objective: During the COVID-19 pandemic, frontline workers have taken to social media platforms to discuss a variety of issues that concern their personal and professional lives. In particular, TikTok's increased prominence as a social media channel has proved significant for enhancing the public presence of healthcare workers and their ability to disseminate content to a wider audience. The ways that healthcare workers use TikTok draws attention to the type of health information disseminated to the public through social media platforms. This provides the public with succinct and often visually entertaining information that may not be otherwise distributed to them directly from elsewhere. This study also provides relevant insights into how social media-TikTok in particular-can be used as a tool for disseminating knowledge about COVID-19 related topics and combatting misinformation by using the credibility of frontline workers. Methods: This study collected a sample of over 2100 TikTok videos posted by healthcare workers that were coded according to the dominant overarching themes. Results: The themes that arose from this sample were: (1) healthcare workers' mental health and working conditions, (2) healthcare heroes/appreciation, (3) criticism against official authorities, (4) countering misinformation, (5) humor/satire, and (6) educational content. Conclusion: Due to the rise in public appreciation for frontline workers, examining the effects of the pandemic through the eyes of frontline workers has drawn attention to their lived realities in various forms. This study provided some insight into how frontline workers use TikTok to disseminate information and education to the public, often relying on their perceived credibility.

SARS-CoV-2-free residual proteins mediated phenotypic and metabolic changes in peripheral blood monocytic-derived macrophages in support of viral pathogenesis.

The large-scale dissemination of coronavirus disease-2019 (COVID-19) and its serious complications have pledged the scientific research communities to uncover the pathogenesis mechanisms of its etiologic agent, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Methods of unveiling such mechanisms are rooted in understanding the viral agent's interactions with the immune system, including its ability to activate macrophages, due to their suggested role in prolonged inflammatory phases and adverse immune responses. The objective of this study is to test the effect of SARS-CoV-2-free proteins on the metabolic and immune responses of macrophages. We hypothesized that SARS-CoV-2 proteins shed during the infection cycle may dynamically induce metabolic and immunologic alterations with an inflammatory impact on the infected host cells. It is imperative to delineate such alterations in the context of macrophages to gain insight into the pathogenesis of these highly infectious viruses and their associated complications and thus, expedite the vaccine and drug therapy advent in combat of viral infections. Human monocyte-derived macrophages were treated with SARS-CoV-2-free proteins at different concentrations. The phenotypic and metabolic alterations in macrophages were investigated and the subsequent metabolic pathways were analyzed. The obtained results indicated that SARS-CoV-2-free proteins induced concentration-dependent alterations in the metabolic and phenotypic profiles of macrophages. Several metabolic pathways were enriched following treatment, including vitamin K, propanoate, and the Warburg effect. These results indicate significant adverse effects driven by residual viral proteins that may hence be considered determinants of viral pathogenesis. These findings provide important insight as to the impact of SARS-CoV-2-free residual proteins on the host cells and suggest a potential new method of management during the infection and prior to vaccination.

Characterizing the Gendered Twitter Discussion of COVID-19 Hoax.

We collected data from Twitter and used content analysis to better understand the gendered discussion around COVID-19 as a hoax. We identified three main categories in the inductive stage of the research: (1) sympathetic to human rights & perceived injustice, (2) invincibility and superiority of COVID hoaxers, (3) conspiracies and/or hidden agendas. The findings of the study show that among all gender groups, the first category is the most dominant (44.4%), the third category is the second most frequent (35.6%), and the last category (19.9%) is the least frequent. However, when the discussion is centered on men (40.2%) and gender and sexual minorities (GSM; 69.6%) groups, the last category is the most dominant with regard to stigmatizing GSM groups by falsely associating them with progressive secret agendas. As for women's group, being sympathetic to human rights and the perceived injustice against them during the pandemic constitute the most dominant category (51.5%). We discuss the implications of the study in the conclusion.

The gendered dimensions of the anti-mask and anti-lockdown movement on social media.

This paper examines the anti-mask and anti-lockdown online movement in connection to the COVID-19 pandemic. To combat the spread of the coronavirus, health officials around the world urged and/or mandated citizens to wear facemasks and adopt physical distancing measures. These health policies and guidelines have become highly politicized in some parts of the world, often discussed in association with freedom of choice and independence. We downloaded references to the anti-mask and anti-lockdown social media posts using 24 search terms. From a total of 4209 social media posts, the researchers manually filtered the explicit visual and textual content that is related to discussions of different genders. We used multimodal discourse analysis (MDM) which analyzes diverse modes of communicative texts and images and focuses on appeals to emotions and reasoning. Using the MDM approach, we analysed posts taken from Facebook and Instagram from active anti-mask and anti-lockdown users, and we identified three main discourses around the gendered discussion of the anti-mask movement including hypermasculine, sexist and pejorative portrayals of "Karen", and appropriating freedom and feminism discourses. A better understanding of how social media users evoke gendered discourses to spread anti-mask and anti-lockdown messages can help researchers identify differing reactions toward pandemic measures.

Investigation of COVID-19 Misinformation in Arabic on Twitter: Content Analysis.

Background: The COVID-19 pandemic has been occurring concurrently with an infodemic of misinformation about the virus. Spreading primarily on social media, there has been a significant academic effort to understand the English side of this infodemic. However, much less attention has been paid to the Arabic side. Objective: There is an urgent need to examine the scale of Arabic COVID-19 disinformation. This study empirically examines how Arabic speakers use specific hashtags on Twitter to express antivaccine and antipandemic views to uncover trends in their social media usage. By exploring this topic, we aim to fill a gap in the literature that can help understand conspiracies in Arabic around COVID-19. Methods: This study used content analysis to understand how 13 popular Arabic hashtags were used in antivaccine communities. We used Twitter Academic API v2 to search for the hashtags from the beginning of August 1, 2006, until October 10, 2021. After downloading a large data set from Twitter, we identified major categories or topics in the sample data set using emergent coding. Emergent coding was chosen because of its ability to inductively identify the themes that repeatedly emerged from the data set. Then, after revising the coding scheme, we coded the rest of the tweets and examined the results. In the second attempt and with a modified codebook, an acceptable intercoder agreement was reached (Krippendorff α≥.774). Results: In total, we found 476,048 tweets, mostly posted in 2021. First, the topic of infringing on civil liberties (n=483, 41.1%) covers ways that governments have allegedly infringed on civil liberties during the pandemic and unfair restrictions that have been imposed on unvaccinated individuals. Users here focus on topics concerning their civil liberties and freedoms, claiming that governments violated such rights following the pandemic. Notably, users denounce government efforts to force them to take any of the COVID-19 vaccines for different reasons. This was followed by vaccine-related conspiracies (n=476, 40.5%), including a Deep State dictating pandemic policies, mistrusting vaccine efficacy, and discussing unproven treatments. Although users tweeted about a range of different conspiracy theories, mistrusting the vaccine's efficacy, false or exaggerated claims about vaccine risks and vaccine-related diseases, and governments and pharmaceutical companies profiting from vaccines and intentionally risking the general public health appeared the most. Finally, calls for action (n=149, 12.6%) encourage individuals to participate in civil demonstrations. These calls range from protesting to encouraging other users to take action about the vaccine mandate. For each of these categories, we also attempted to trace the logic behind the different categories by exploring different types of conspiracy theories for each category. Conclusions: Based on our findings, we were able to identify 3 prominent topics that were prevalent amongst Arabic speakers on Twitter. These categories focused on violations of civil liberties by governments, conspiracy theories about the vaccines, and calls for action. Our findings also highlight the need for more research to better understand the impact of COVID-19 disinformation on the Arab world.

Sex Workers' Lived Experiences With COVID-19 on Social Media: Content Analysis of Twitter Posts.

BACKGROUND: The COVID-19 pandemic has drawn attention to various inequalities in global societies, highlighting discrepancies in terms of safety, accessibility, and overall health. In particular, sex workers are disproportionately at risk due to the nature of their work and the social stigma that comes alongside it. OBJECTIVE: This study examines how public social media can be used as a tool of professional and personal expression by sex workers during the COVID-19 pandemic. We aimed to explore an underresearched topic by focusing on sex workers' experiences with the ongoing COVID-19 pandemic on the social media platform Twitter. In particular, we aimed to find the main issues that sex workers discuss on social media in relation to the COVID-19 pandemic. METHODS: A literature review followed by a qualitative analysis of 1458 (re)tweets from 22 sex worker Twitter accounts was used for this study. The tweets were qualitatively coded by theme through the use of intercoder reliability. Empirical, experimental, and observational studies were included in this review to provide context and support for our findings. RESULTS: In total, 5 major categories were identified as a result of the content analysis used for this study: concerns (n=542, 37.2%), solicitation (n=336, 23.0%), herd mentality (n=231, 15.8%), humor (n=190, 13.0%), and blame (n=146, 10.0%). The concerns category was the most prominent category, which could be due to its multifaceted nature of including individual concerns, health issues, concerns for essential workers and businesses, as well as concerns about inequalities or intersectionality. When using gender as a control factor, the majority of the results were not noteworthy, save for the blame category, in which sexual and gender minorities (SGMs) were more likely to post content. CONCLUSIONS: Though there has been an increase in the literature related to the experiences of sex workers, this paper recommends that future studies could benefit from further examining these 5 major categories through mixed methods research. Examining this phenomenon could recognize the challenges unique to this working community during the COVID-19 pandemic and potentially reduce the widespread stigma associated with sex work in general.

When Science Becomes Embroiled in Conflict: Recognizing the Public's Need for Debate while Combating Conspiracies and Misinformation.

Most democracies seek input from scientists to inform policies. This can put scientists in a position of intense scrutiny. Here we focus on situations in which scientific evidence conflicts with people's worldviews, preferences, or vested interests. These conflicts frequently play out through systematic dissemination of disinformation or the spreading of conspiracy theories, which may undermine the public's trust in the work of scientists, muddy the waters of what constitutes truth, and may prevent policy from being informed by the best available evidence. However, there are also instances in which public opposition arises from legitimate value judgments and lived experiences. In this article, we analyze the differences between politically-motivated science denial on the one hand, and justifiable public opposition on the other. We conclude with a set of recommendations on tackling misinformation and understanding the public's lived experiences to preserve legitimate democratic debate of policy.

Investigating Public Discourses Around Gender and COVID-19: a Social Media Analysis of Twitter Data.

We collected over 50 million tweets referencing COVID-19 to understand the public's gendered discourses and concerns during the pandemic. We filtered the tweets based on English language and among three gender categories: men, women, and sexual and gender minorities. We used a mixed-method approach that included topic modelling, sentiment analysis, and text mining extraction procedures including words' mapping, proximity plots, top hashtags and mentions, and most retweeted posts. Our findings show stark differences among the different genders. In relation to women, we found a salient discussion on the risks of domestic violence due to the lockdown especially towards women and girls, while emphasizing financial challenges. The public discourses around SGM mostly revolved around blood donation concerns, which is a reminder of the discrimination against some of these communities during the early days of the HIV/AIDS epidemic. Finally, the discourses around men were focused on the high death rates and the sentiment analysis results showed more negative tweets than among the other genders. The study concludes that Twitter influencers can drive major online discussions which can be useful in addressing communication needs during pandemics.

A thematic analysis of Instagram's gendered memes on COVID-19.

We investigate the gendered use of Instagram memes on COVID-19 using a mixed-analysis approach. We find that memes referencing women are mostly related to community support and healthcare, which often express gratitude for frontline workers, while the majority of memes on men refer to news and promotion as well as suffering due to the high death rates and other financial hardships. As for sexual and gender minorities, memes mostly mention community support similar to the case of the memes referencing women. We argue that internet memes offer insight into ongoing trends in the public's perceptions of pandemics, and they should be further examined because they often communicate vital information on gender groups and public health.

COVID-19 and the Gendered Use of Emojis on Twitter: Infodemiology Study.

BACKGROUND: The online discussion around the COVID-19 pandemic is multifaceted, and it is important to examine the different ways by which online users express themselves. Since emojis are used as effective vehicles to convey ideas and sentiments, they can offer important insight into the public's gendered discourses about the pandemic. OBJECTIVE: This study aims at exploring how people of different genders (eg, men, women, and sex and gender minorities) are discussed in relation to COVID-19 through the study of Twitter emojis. METHODS: We collected over 50 million tweets referencing the hashtags #Covid-19 and #Covid19 for a period of more than 2 months in early 2020. Using a mixed method, we extracted three data sets containing tweets that reference men, women, and sexual and gender minorities, and we then analyzed emoji use along each gender category. We identified five major themes in our analysis including morbidity fears, health concerns, employment and financial issues, praise for frontline workers, and unique gendered emoji use. The top 600 emojis were manually classified based on their sentiment, indicating how positive, negative, or neutral each emoji is and studying their use frequencies. RESULTS: The findings indicate that the majority of emojis are overwhelmingly positive in nature along the different genders, but sexual and gender minorities, and to a lesser extent women, are discussed more negatively than men. There were also many differences alongside discourses of men, women, and gender minorities when certain topics were discussed, such as death, financial and employment matters, gratitude, and health care, and several unique gendered emojis were used to express specific issues like community support. CONCLUSIONS: Emoji research can shed light on the gendered impacts of COVID-19, offering researchers an important source of information on health crises as they happen in real time.

Bots as Active News Promoters: A Digital Analysis of COVID-19 Tweets

In this study, we examined the activities of automated social media accounts or bots that tweet or retweet referencing #COVID-19 and #COVID19. From a total sample of over 50 million tweets, we used a mixed method to extract more than 185,000 messages posted by 127 bots. Our findings show that the majority of these bots tweet, retweet and mention mainstream media outlets, promote health protection and telemedicine, and disseminate breaking news on the number of casualties and deaths caused by COVID-19. We argue that some of these bots are motivated by financial incentives, while other bots actively support the survivalist movement by emphasizing the need to prepare for the pandemic and learn survival skills. We only found a few bots that showed some suspicious activity probably due to the fact that our dataset was limited to two hashtags often used by official health bodies and academic communities.